The invention relates to a full-season artificial breeding method of largemouth bass. The method includes the steps of selection and stocking of bass parents, low-temperature stimulation, parent fishintensive cultivation, temperature rise stimulation of gonad development, hormone injection, fry production and the like. The method carries out artificial breeding of largemouth bass in non-breedingseason under the condition of artificial control for the first time, breaks through the limitation that the bass can only be bred in spring in the past, realizes full-season breeding of the largemouthbass; the method can control the fry production and the fish market time of the largemouth bass, and solves the problems of market dyspepsia, low selling price and the like caused by centralized listing; and the method breaks through seasonal and temperature restrictions, provides large-size fries in the breeding season, shortens the breeding and pond storage time of the largemouth bass, and solves the problem that the old fish stored in ponds for a long time is easy to suffer from diseases.