The invention discloses a co-production novel process of tetramethylol melamine. According to the co-production novel process, the tetramethylol melamine and hexahydroxymethyl melamine are jointly produced, and through on-site preparation and use of more than 60% high concentration formaldehyde, and tetrahydroxy mother liquor and hexahydroxy mother liquor are recycled to produce the hexahydroxymethyl melamine. According to the co-production novel process of the tetramethylol melamine, the problem of the high cost of producing the tetramethylol melamine alone is solved, and zero pollution discharge is further realized at the same time.