The invention relates to a porous biomimetic cervical interbody fusion cage and a manufacturing method, and belongs to the field of polymer materials and biomedical engineering. The biomimetic cervical interbody fusion cage is mainly made of poly aryl ether ketone materials. An arc is arranged at the top of biomimetic cervical interbody fusion cageand is matched with the physiological arc of a cervical spine; anti-skid backward serrations are arranged on the upper surface and the lower surface, meanwhile, the main body contains a plurality of through biomimetic holes, the two adjacent rows ofthe bionic holes are arranged in a staggered mode, and the biomimetic holes are internally provided with a pore structure similar to the human cancellous bone structure. According to the porous biomimetic cervical vertebra fusion device, it is ensured that the fusion cage has sufficient mechanical strength, and the biomimetic holes penetrating up and down can further provide a good microenvironment for the growth of tissues, and the long-term stability of the cervical surgical segment is facilitated. The porous biomimetic cervical interbody fusion cage has a broad application prospect in bonerepair, bone transplantation, bone fixation and other fields.