The present invention discloses a highly dry and comfortable all-cotton fabric sanitary pad. The highly dry and comfortable all-cotton fabric sanitary pad comprises skin-friendly dry and comfortable all-cotton fabric, an absorption core body, two protective wings and a bottom film, the skin-friendly dry and comfortable all-cotton fabric comprises a water repellent area and an absorption area, andthe water repellent area is prepared by using a water repellent technology; the absorption core body is a quick absorption core body, the quick absorption core body is a compound core body provided with fluff pulp with a plurality of flow guide holes and a water-absorbing polymer material, and the absorption core body is a quick absorption core body, and can quickly absorb and lock water. Mesh-shaped pure cotton non-woven fabric is subjected to a special treatment to obtain the mesh-shaped semi-water-repellent pure cotton non-woven fabric as the skin-friendly dry and comfortable all-cotton fabric, the quick absorption core body is combined to play a synergistic effect, so that quick absorption of menstrual blood is realized, meanwhile, bottom layer leakage is prevented, reverse osmosis ofthe skin-friendly dry and comfortable all-cotton fabric is effectively avoided, and the pad surface is kept dry and comfortable.