The invention provides a zero-emission treatment process and device for papermaking wastewater. In the process, the papermaking wastewater is firstly subjected to grid treatment and flocculation treatment; then biochemical treatment is carried out by a hydrolysis acidification/UASB/MBR integrated manner; the treated tail water is subjected to advanced treatment by a zero-emission treatment unit consisting of ultrafiltration and nanofiltration membranes, a three-dimensional membrane bio-electrode, and a reverse osmosis membrane. In the whole process, wastewater and solid waste in each treatmentunit are subjected to corresponding advanced treatment, the whole system runs smoothly, and a purpose of low-cost zero-emission treatment of papermaking wastewater is achieved.