The invention relates to a ceramic dielectric filled waveguide filter. The ceramic dielectric filled waveguide filter adopts a staggered-resonant cavity topology structure. The filter includes a ceramic dielectric block, a resonant cavity group, grooves, an input port and an output port, wherein the ceramic dielectric block is provided with the resonant cavity group, the resonant cavity group includes multiple resonant cavities arranged in parallel in a staggered manner in two vertical layers, one individual resonant cavity of the upper layer is located on a central axis between two adjacent resonant cavities in the lower layer, a groove used for adjusting the coupling amount of the adjacent cavities is arranged between every two adjacent resonant cavities in the same layer, a groove usedfor adjusting the coupling amount of the adjacent cavities is arranged between two resonant cavities at the same side end portions of different layers, and the cross-coupling amount of two interlacedresonant cavities on the same diagonal lines of different layers is jointly adjusted through two interlaced grooves on another diagonal line. The filter is advantaged in that multiple cross-coupling structures are achieved through the staggered resonant cavities, a variety of cavity-to-cavity coupling effects are achieved through the grooves, and the filter with left and right transmission zero asymmetry is achieved.