The invention discloses a dust removal device for a power distribution station. The dust removal device comprises a main machine, an air extracting pump and an exhaust pump. An exhaust pipe of a hollow structure is connected to the air extracting pump through a pipeline. An air spraying disc is connected to the end, away from the air extracting pump, of the exhaust pipe through threads in a screwed mode, the exhaust pipe is sleeved with a dust suction pipe, and the dust suction pipe is connected with the exhaust pump through a pipeline. A dust suction disc is arranged at the end, away from theair extracting pump, of the dust suction pipe. According to the dust removal device, dust dried and fixed to substation equipment is swept off by a brush sweeper on the air spraying disc, the dust suction disc further sucks away the swept-off dust, and the problems that flying dust falls to the rest places of equipment to cause a short circuit are avoided. Dust existing in holes or narrow spacesis raised in an air blowing form, and then the raised dust is removed completely through the dust suction disc. Through the dust removal device, the effect of equipment cleaning is achieved under thecircumstance of electrification, not outage operation is needed, safety of operators in the cleaning process can be ensured, and meanwhile continuous power utilization in the area is not influenced.