The invention discloses a steel plate combined shear wall with honeycomb partition plates arranged in a staggered manner and a preparation method. The steel plate combined shear wall comprises two outer wrapping steel plates which are arranged in parallel, two honeycomb partition plate groups which are symmetrically distributed are arranged between the two outer wrapping steel plates, and the honeycomb partition plate groups are perpendicular to the outer wrapping steel plates; the honeycomb partition plate groups comprise multiple partition plates distributed side by side, and each partitionplate is provided with a group of honeycomb holes which are vertically and evenly distributed; the honeycomb holes formed in every two adjacent partition plates are distributed in a staggered manner;and each partition plate comprises two partition single plates which are fixedly welded, and each partition single plate is provided with a group of semi-honeycomb openings which are vertically and evenly distributed. The steel plate combined shear wall has the characteristic that the integral rigidity of the shear wall can be effectively improved.