The invention discloses a monitoring method with cooperative work of multiple sensors and a system using the method to work. The method includes the following steps: different environment informationis collected by using different kinds of sensors; the sensors are classified by power consumption values into at least two kinds of low-power consumption sensors and high-power consumption sensors; after the system is woken up, the low-power consumption sensors and the high-power consumption sensors samples with set sampling periods T1 and T2; if measured values A1 of the low-power consumption sensors reach or exceed a set alarm threshold A0, real-time sampling of the low-power consumption sensors and the high-power consumption sensors is triggered until the system is in a normal state, the normal state is that the A1 is less than the A0, and measured values B1 of the high-power consumption sensors are less than a set alarm threshold B0. The advantages of the monitoring method and system of the technical scheme of the invention greatly reduces the energy consumption of the system and emergency events can be more comprehensively, accurately and timely learned.