The invention discloses a large-scale enterprise supply and demand side matching method based on a three-way decision. The method comprises the following steps: converting actual values and ideal values with semantic information of two sides into corresponding interval numbers; calculating each matching main body to generate an initial satisfaction matrix; establishing a three-branch matching matrix based on the three-branch decision according to the satisfaction threshold, and dividing the matching pairs into three parts; establishing a multi-target model from the perspectives of the satisfaction degree of the matching subject, the fairness of the matching scheme and the overall benefit to obtain an optimal matching result and a corresponding quantitative relationship; updating the cooperation stability and satisfaction of the matching subject; and solving the multi-target model again until the maximum number of iterations is reached, and at the moment, obtaining a convergence resultwhich is a final matching result. According to the method, a many-to-many two-party matching result can be obtained, the satisfaction evaluation mode is further improved, the accuracy of satisfactionevaluation under a long-term cooperation relationship is improved, the status of two parties in cooperation is balanced, and the overall benefit of an enterprise is improved.