The invention provides a low-voltage transformer area operation state multidimensional influence factor comprehensive evaluation method and system, and the method comprises the steps: S1, obtaining data from different power data management systems, and determining a low-voltage transformer area operation state multidimensional influence factor set U according to an expert experience method; S2, performing missing value and noise preprocessing on the multi-dimensional influence factor set data, the data quality being improved, and providing a data basis for low-voltage transformer area operation state evaluation; S3, normalizing the multi-dimensional influence factors, analyzing the weights of the influence factors by using an order relation method, and determining the influence degrees ofdifferent influence factors on the operation state of the transformer area; and S4, summing the products of the weight values of the influence factors and the normalization processing values to obtainan overall score of the operation state of the low-voltage transformer area, and determining the operation state of the transformer area. The method can effectively evaluate the operation state of the low-voltage transformer area, obtains the overall score of the low-voltage transformer area, and can lay a foundation for improving the lean management level of the transformer area, actively carrying out the operation and maintenance, and achieving the loss reduction and efficiency improvement of the transformer area.