The invention belongs to the technical field of marine wave energy power generation, and particularly relates to a moon pool array float wave energy conversion device self-adapted to sea conditions. According to moon pool array float wave energy conversion device, compared with traditional application, automatic replacement of a float is realized, a replacement period is shortened, and the difficult problemfor replacing the float underwater is solved. By changing a working mode of a hydraulic cylinder float, a moon pool array float is better coupled with the sea conditions, wave energy conversion power is improved, and at the same time, accuracy and perfection of application data are better guaranteed. The automatic replacement function of the hydraulic cylinder float through a hydraulic drive control module is achieved, and a parameter comparison between experimental variables is realized, the replacement period which can be avoided in actual work can be saved, an accurate test information record through a GPS positioning module can be obtained, and double guarantee is provided for accuracy of application of a moon pool in the actual work.