The invention discloses a method for preparing a lithium ion battery TiO2 nano-array limited-domain antimony oxide anode and an anode. The anode comprises a conductive current collector substrate, porous titanium dioxide grown on the substrate and composed of a nanopore array and mesh micron pores, and Sb2O3 filling in nano-array pipelines and the mesh micron pores. Since the Sb2O3 enters the nanopore array and the mesh micron pores of the TiO2 substrate, a directional accommodation space can be provided for Sb2O3 volume expansion during a charge-discharge process so as to prevent the Sb2O3 from falling and lossing activity. The TiO2 has an one-dimensional stable conductive path, provides a guarantee for the ion and electron transport of the composite anode, and also has a theoretical specific capacity of 170 mAh.g-1. The nano-scale Sb2O3 also facilitates the release of lithium intercalation stress and shortens ion and electron migration paths.