The invention provides a full-automatic guide wire cutting machine, and belongs to the field of electric power construction tools. The full-automatic guide wire cutting machine comprises a machine base, a rotary table arranged on the machine base, a rotary drive mechanism connected with the rotary table, clamping mechanisms arranged on the front side and the back side of the rotary table, and a peeling and cutting mechanism arranged on the rotary table, wherein a rotary shaft of the rotary table is parallel to the front-and-back direction; a cable passing hole is formed in the middle of the rotary table; and the peeling and cutting mechanism comprises a cutter holder, a cutter drive structure connected with the cutter holder and the rotary table and used for enabling the cutter holder to move in the radial direction of the rotary table, two cutters arranged on the cutter holder and distributed in the front-and-back direction, and a shifting rod arranged on the cutter holder and locatedbetween the two cutters. According to the full-automatic guide wire cutting machine provided by the invention, no manual participation is needed in the aluminum twisted wire cutting and aluminum twisted wire stripping processes, in addition, the equipment is simple in structure and stable in cutting effect, and the peeling efficiency can be effectively improved.