The invention relates to the technical field of oil-gas exploration and development. The invention discloses a beneficial reservoir evaluation and prediction technology based on rock-field-flow coupling. The method comprises the following steps: recovering reservoir source region properties and hydrodynamic condition characteristics by integrating bedrock and stratum petrology characteristics inside and outside the basin; recognizing the characteristics of the diagenetic field; dividing different source reservoirs, quantitatively recovering diagenetic-pore evolution processes of reservoirs ofdifferent source reservoirs; determining a space-time coupling relationship between reservoir diagenetic-pore evolution and filling of fluids such as oil gas, overpressure and organic acid; anddetermining main control factors of reservoir physical properties, analyzing cause mechanisms, distribution rules and control factors of reservoir forming main control factors, predicting longitudinal and transverse distribution of the reservoir forming main control factors, and predicting favorable reservoir distribution in a source reservoir area by superposing the distribution of the reservoir forming main control factors.