The invention provides a method for controlling adhesives suitable for a large-scale coated paper machine. According to the method, three kinds of adhesive control agents including a passivating agent, a fixing agent and a combined dispersant are added to a wet end system of the paper machine simultaneously, wherein the passivating agent is added to the outlet of a coating dry-loss fluffer in thewet end system, the fixing agent is added to the pump washing side of an outlet pump of a dry loss metering tank in the wet end system, and the combined dispersant is added to white water in the wet end system; and the passivating agent is a cationic polymer with low charge density and low molecular weight, the fixing agent is a cationic polymer with medium charge density and medium molecular weight, and the combined dispersant is a composite which is obtained through mixing of an anionic dispersant and a nonionic surfactant. The formation amount and size of the adhesives can be controlled effectively, the adhesive control agents have a stable effect, the cleanliness and stability of the wet end system are improved, the problems of holes and paper breaks caused by deposition of the adhesives are solved, and the purposes of improvement of the operating efficiency of the paper machine and improvement of the paper quality are achieved.