This nonaqueous electrolyte secondary battery is provided with an electrode body that is obtained by alternately laminating a plurality of positive electrodes and a plurality of negative electrodes, with separators being interposed therebetween. Each separator is configured of a porous resin substrate and a porous heat-resistant layer that is formed on one surface of the resin substrate and has alarger surface roughness than the resin substrate. The electrode body comprises: bonding particles that bond a negative electrode and a heat-resistant layer with each other; and bonding particles thatbond a positive electrode and a resin substrate with each other. The mass of the bonding particles per unit area in a first interface between the negative electrode and the heat-resistant layer is larger than the mass of the bonding particles per unit area in a second interface between the positive electrode and the resin substrate.