A vending machine has a cabinet (2) internally defining a dispensing compartment (3) that is closed by a front door (6) and houses a plurality of dispensing trays (8), each of which supports a plurality of products and is slidably engaged in a guide device defined by a pair of elongated guides (11), each of which is coupled to the cabinet (2) through a front tooth (13) and a rear tooth (14) and isprovided with a retractable spring-loaded locking pin (17) movable between a coupling position and a release position with respect to the cabinet (2).