The invention discloses micro-droplet spray equipment with a multi-nozzle spray head. The micro-droplet spray equipment comprises the multi-nozzle spray head, a workbench, an XY-axis moving device, aZ-axis moving device, a solution tank, a supporting frame and a control system, wherein the multi-nozzle spray head is mounted on the Z-axis moving device and positioned above the workbench; the workbench is mounted on the XY-axis moving device; the supporting frame is used for the mounting of all components; the multi-nozzle spray head comprises a main body, a mandrel, a motor and a multi-nozzlestructure; a plurality of solution channels which consist of solution inflow holes, ring-shaped grooves, solution outflow holes and nozzle channels are arranged in the multi-nozzle spray head; and nozzles are arranged at the outlets of the solution channels and uniformly distributed in a ring-shaped manner. Through the design that the exterior of the nozzles are stationary and the interiors of thenozzles are rotary, solution input ports can be fixed, and the change of spray materials can be rotationally completed at the output end; the complexity of a conventional multi-nozzle mechanism can be reduced; the operation can be simple; and furthermore, the problems that a solution supply pipe twists and the positioning is incorrect during the spray head conversion process of the conventional multi-nozzle device can be solved.