The invention discloses a clamp structure for machining V-shaped grooves in ends of matching surfaces of glass molds, and belongs to the technical field of tool clamps. The clamp structure comprises glass mold limiting block fixing bases and glass mold limiting blocks. A glass mold first limiting cavity is formed in the front side of the left end of each glass mold limiting block, a glass mold second limiting cavity is formed in the front side of the right end of each glass mold limiting block, and a clamping strip supporting threaded rod base is arranged between each glass mold first limitingcavity and the corresponding glass mold second limiting cavity. The rear end of each clamping strip supporting threaded rod and the rear side of the corresponding glass mold limiting block fixing base are fixed, and the front end of each clamping strip supporting threaded rod stretches towards the front of the corresponding clamping strip supporting threaded rod base in a cantilever state. The middle of each clamping strip is supported at the front end of the corresponding clamping strip supporting threaded rod, the left end of each clamping strip is a cantilever end, and the right end of each clamping strip is a cantilever end as well. Locating adjusting pieces are arranged on the left or right cavity wall of each glass mold first limiting cavity and the left or right cavity wall of thecorresponding glass mold second limiting cavity. The number of the glass molds which are clamped at one time is increased so as to achieve the ideal integration effect, the clamping efficiency is improved, the universalization is high, the structure is simple, and the clamp structure can be conveniently and rapidly matched with a milling machine platform of a milling machine.