The invention provides a sealing structure for a vertical water-cooling wall nozzle tube screen and belongs to the field of boiler water-cooling wall fabrication. The sealing structure for the vertical water-cooling wall nozzle tube screen is mainly to solve the problems that curved water-cooling tubes inside a four-corner corner cut vertical water-cooling wall nozzle tube screen and an original tube screen are heated inconsistently in working, expansion difference results in stress concentration at the pull-out tube root portion, and fin cracking results in tube inside gas leakage. The main technical scheme of the sealing structure for the vertical water-cooling wall nozzle tube screen is that four corners of the vertical water-cooling wall nozzle tube screen are provided with two sets ofcurved water-cooling tube screens correspondingly, and the two sets of curved water-cooling tube screens are oppositely arranged along diagonal lines of the vertical water-cooling wall nozzle tube screen, the two sides of a vertical segment A inside each curved water-cooling tube are provided with one seal flat steel correspondingly, each seal flat steel is welded between one curved water-coolingtube and one vertical water cooling tube adjacent to the corresponding curved water-cooling tube, each set of curved water-cooling tube screen is provided with one seal box, and each seal box is fixedly connected at the joint of N vertical segments A and N curved segments inside the corresponding curved water-cooling tube screen. The sealing structure for the vertical water-cooling wall nozzle tube screen is mainly used for a water cooling wall arrangement structure inside a four-corner boiler.