The invention discloses a power distribution network power supply capability evaluation method and device based on an energy information interaction center. The method comprises the following steps: acquiring load of a feeder line or a main transformer in a power supply area; under the assumption that the feeder line or the main transformer has an N-1 fault, acquiring other feeder lines or main transformers capable of bearing the load; judging whether the load can be transferred to the other feeder lines or main transformers; if not, carrying out power support on an overload element through the energy information interaction center to judge whether the other feeder lines or main transformers can bear the load or not; if one of the two judgment results is yes, determining that the feeder lines or the main transformers pass the N-1 test; and under the condition that all the feeder lines and the main transformers pass the N-1 test, determining that the maximum load of the power supply area is the maximum power supply capacity. The problem that it is difficult to realize maximization of the power supply capacity of the power distribution network in the prior art is solved.