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发明公开
CN110585224A 知母皂苷BⅠ、知母皂苷ⅠA、知母皂苷AⅢ在制备抗认知障碍疾病药物中的应用 无效 - 驳回

知母皂苷BⅠ、知母皂苷ⅠA、知母皂苷AⅢ在制备抗认知障碍疾病药物中的应用
摘要：
本发明涉及医药技术领域，具体公开知母皂苷BⅠ、知母皂苷ⅠA、知母皂苷AⅢ在制备抗认知障碍疾病药物中的应用。本发明提供了知母皂苷BⅠ、知母皂苷ⅠA、知母皂苷AⅢ新的医药用途，经药效学研究表明，知母皂苷BⅠ、知母皂苷ⅠA、知母皂苷AⅢ具有显著地抗认知障碍的作用，因此可用于制备抗认知障碍疾病药物。由于药物的活性成分单一，药物制备过程中质量易控，可实施性强，为将来药物开发中低成本和高产率的制备奠定了基础。另外，此类药物的制剂形式多样，可根据患者需要制成不同制剂形式，还可作为抗认知障碍的食品和保健品的活性成分，便于不同疾病患者服用。本发明新型抗认知障碍活性成分的发现，具有非常好的开发应用前景。
摘要（英）：

The invention relates to the technical field of medicine, and concretely discloses application of timosaponin BI, timosaponin IA and timosaponin AIII to preparation of anti-cognitive-impairment disease medicine. The invention provides a novel medicine purpose of the timosaponin BI, the timosaponin IA and the timosaponin AIII. The pharmacodynamics study proves that the timosaponin BI, the timosaponin IA and the timosaponin AIII have an obvious anti-cognitive-impairment effect, so that the timosaponin BI, the timosaponin IA and the timosaponin AIII can be used for preparing the anti-cognitive-impairment disease medicine. An active ingredient of the medicine is single, so that the quality is easy to control in the medicine preparation process; the implementability is high; and the foundationis laid for the low-cost and high-yield preparation in future medicine development. In addition, the preparation forms of the medicine are various; different preparation forms can be made according tothe requirements of patients; the timosaponin BI, the timosaponin IA and the timosaponin AIII can also be used as the active ingredients of anti-cognitive-impairment food and health care products; and the taking by patients with different diseases is convenient. Through the novel anti-cognitive-impairment active ingredient discovery, good development and application prospects are realized.

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