The invention relates to a grouting stopping sealing and blocking device and a grouting anchor cable hole sealing grouting stopping method, belongs to the technical field of grouting anchor cable construction, and solves the problems that when an existing grouting stopping plug is used for broken surrounding rock grouting stopping, the grouting stopping effect of slurry is poor, slurry seepage caneasily occur, and the poor reinforcing support effect is further caused. The grouting stopping sealing and blocking device comprises a foaming agent spray head and a foaming agent injection pipe, wherein one end of the foaming agent injection pipe is connected with the foaming agent spray head; the other end of the foaming agent injection pipe is connected with the foaming agent storage tank; each of the foaming agent spray head and the foaming agent injection pipe can be arranged on the grouting anchor cable in a sleeving way and can move in a drill hole along the grouting anchor cable; anda curing foam body formed by the foaming agent sprayed out from the foaming agent spray head can be in contact with the hole wall to complete the grouting stopping sealing and blockage. The grouting stopping sealing and blocking device and the grouting anchor cable hole sealing grouting stopping method have the advantages that the sealing hole sealing and blockage in an expected position is realized; the slurry seepage during the grouting in the broken surrounding rock in a shallow part of a roadway is effectively prevented; the engineering is reliable; the environmental-friendly and energy-saving effects are achieved; and the operation is simple and convenient, and the like.