The invention relates to a pumped storage unit sensor threshold setting method based on multiple regression analysis. The pumped storage unit sensor threshold setting method comprises the steps: carrying out the monitoring and calculation of real-time data through a data collection module, obtaining a signal of each sensor, and extracting three groups of data: the maximum value, the minimum valueand the median value of a signal in each period; taking a large amount of historical data of the unit as sample data for sensor threshold research; and using a multiple regression analysis method to establish a mathematical model, and approximating the actual operation condition of the unit, so as to calculate the reasonable range of the threshold of each sensor of the unit through scientific analysis.