The present invention discloses a chlorine dioxide-based fruit fresh-keeping package and a preparation method thereof. The fresh-keeping package comprises a cylindrical package composed of three layers of fresh-keeping layers, and a center of the cylinder forms a hollow storage space. An inner layer of the fresh-keeping layer is a natural fresh-keeping layer, a middle layer is a slow-release chlorine dioxide fresh-keeping layer, and an outermost layer is a fluidized ice fresh-keeping layer. Materials for preparing the natural fresh-keeping agent fresh-keeping paper comprise a carrier, a water-absorbing agent, a natural fresh-keeping agent and a binder; and materials for preparing the slow-release type chlorine dioxide fresh-keeping layer comprise sodium chlorite microcapsule powder, citricacid, oxalic acid, lactic acid and formic acid loaded on natural zeolite and a transition metal catalyst. During storage process, continuous release and fresh-keeping time of chlorine dioxide is long-lasting, and at the same time, under cold storage and fresh-keeping synergistic effects of natural fresh-keeping agent sterilization and fresh-keeping fluidized ice, storage time of fruits is significantly prolonged and storage quality is significantly improved. At the same time, an application of the fluidized ice outside of the package can reduce collision and squeezing of the fruits during transportation and storage.