The invention relates to a high-strength adhesive rubber sealing strip self-lubricating material and a preparation method thereof. The material comprises the following components in parts by weight: 35 parts of EPDM, 30 parts of PP, 35 parts of paraffin oil, 2.0 parts of a self-lubricating agent, 2.0 parts of a vulcanizing agent DCP, 3.0 parts of an auxiliary vulcanizing agent TAIC, 1.5 parts of aperoxide initiator, 2.0 parts of TAIC and 0.5 part of a polymerization inhibitor. The preparation method mainly comprises the following steps: firstly, carrying out high-temperature mixing on EPDM, PP and paraffin oil, and carrying out granulation for later use; mixing the particles with odorless DCP and TAIC, performing dynamic vulcanization through a double-screw extruder at the vulcanizing temperature of 180-190 DEG C and the rotating speed of 300-500 rpm, and carrying out granulation after vulcanization; and mixing the granules prepared in the step B with a peroxide initiator, a polymerization inhibitor and a self-lubricating agent, and then performing extrusive blending granulation at the extrusion temperature of 170 DEG C or below to form the finished TPV bonding material. By meansof the self-made self-lubricating agent, the problem that a large amount of whiteness is formed on the surface of the TPV is solved.