The invention provides an experimental device, an experimental system and an experimental method for the seepage performance of a self-expansion sand control screen. The device comprises a cylinder body and the self-expansion sand control screen located in the cylinder body, and the self-expansion sand control screen comprises a base tube and a self-expansion sleeve sleeved on the base tube; the cylinder body is provided with a fluid inlet and a measuring port; the measuring port is provided with an ejector rod and a gravity sensor connected with the ejector rod; and a base is arranged at theopen end of the cylinder body, the base is in sealing connection with the end portion of the base tube, and the base is provided with a fluid outlet. The method comprises the following steps: heatingan experimental fluid to expand the self-expansion sleeve, recording the pressure of the fluid inlet, the pressure of the inner cavity of the base tube and the flow of the fluid outlet in and/or afterthe process of expanding the self-expansion sleeve in place, and calculating the permeability in process of expanding the self-expansion sand control sleeve in place; and obtaining the expansion force through the gravity sensor. The seepage performance of the self-expansion sleeve after expansion can be measured, and the expansion force of the self-expansion sleeve after expansion in place can also be measured.