The present invention relates to the field of medical devices and particularly discloses a four-branch artificial blood vessel assembly. The four-branch artificial blood vessel assembly comprises a blood vessel main body provided with four branch blood vessels and also comprises a semi-open type blocking device; the semi-open type blocking device comprises a shell body, the shell body is internally provided with a stent passage for a support to pass through, a pressure cavity for accommodating fluid and an elastic film for separating the stent passage from the pressure cavity, and the shell body is provided with a circulation port communicating with the pressure cavity and used for the fluid to enter and exit; a proximal port of the blood vessel main body is connected with the shell body and communicates with the stent passage; and after the pressure cavity is filled with the fluid to promote the elastic film to expand towards a direction of the stent passage and block the stent passage. The four-branch artificial blood vessel assembly can complete operations without adopting deep hypothermic circulatory arrest under a condition of placing a stent anterogradely, thus reduces postoperative complications and improves operation effect.