The invention discloses an anti-interference method and device for an automatic regression test, computer equipment and a storage medium, and the method comprises the steps: recording a tracking identification of a current flow during flow recording; when a random number is generated, establishing an association relationship between a tracking identifier and a random number; when the flow is replayed, obtaining a random number associated with a tracking identifier according to the currently replayed tracking identifier; and replaying the flow according to the random number. The embodiment of the invention provides an anti-interference scheme for an automatic regression test. The association relationship between the tracking identifier and the random number can be recorded when the flow isrecorded, and the random number used by the current flow is determined according to the recorded association relationship when the flow is replayed, so that the random number used when the flow is replayed is the same as the random number used when the flow is recorded, and the automatic regression test reliability is improved.