The invention relates to the technical field of power supply control, in particular to a multi-phase DCDC power supply control circuit with self-adaptive adjustment of output voltage. The circuit comprises a CPU core power supply, a processor, a self-adaptive voltage positioning circuit and a digital loop compensation circuit. The CPU core power supply adjusts the output voltage according to the comparison result of the obtained detection voltage of the processor and a set voltage value, the digital loop compensation circuit compensates the output voltage according to the comparison result ofthe external voltage of the processor and the set voltage value, and the self-adaptive voltage positioning circuit adjusts the set voltage value according to the detection circuit. In the prior art, when the output current of the core power supply to the processor rapidly changes, the corresponding speed of the core power supply is insufficient, and the output voltage fluctuation is caused to be too large. Compared with the prior art, through the cooperation of the CPU core power supply, the self-adaptive voltage positioning circuit and the digital loop compensation circuit, when the output current changes rapidly, the output voltage can be kept stable.