The embodiment of the invention belongs to the technical field of information security, and relates to a data security processing method, which comprises the steps of obtaining a symmetric key of which the complexity is matched with a to-be-encrypted data type according to the to-be-encrypted data type of request data, the symmetric key comprising a randomly generated character string; encryptingthe request data by using a message digest algorithm to obtain first encrypted data, and encrypting the request data by using a symmetric key to obtain second encrypted data; receiving a public key sent by the server, and encrypting the symmetric key by using an asymmetric encryption algorithm to obtain an encryption key; and sending the first encrypted data, the second encrypted data and the encryption key to a server. The invention further provides a data security processing device, a computer system and a storage medium. The request data can be encrypted, and the data security is improved.