The invention relates to a combined cooling heating and power supply and demand balance optimization scheduling method considering an energy supply side and a demand side. The method comprises the steps that S1, an energy supply side model is established according to the running state of a combined cooling heating and power system; S2, establishing a demand side demand response control model according to user load characteristics; S3, obtaining an energy supply flexibility index and an energy use flexibility index; S4S4, establishing a cooling, heating and power combined supply and demand balance optimization scheduling model; the model takes the electric energy interaction cost of a microgrid and an external power grid, the gas cost and the equipment maintenance cost as the total operation cost; the root mean square of the electric energy and cold/heat energy flexibility indexes is used as a system comprehensive flexibility index; and S5, solving the established combined cooling heating and power supply and demand balance optimization scheduling model by using a multi-objective particle swarm algorithm, and selecting the most appropriate solution according to the actual situation.According to the method, two types of flexible resources of the energy supply side and the demand side are comprehensively considered, flexible supply and demand balance is constructed from the perspectives of supply and demand complementation and multi-energy complementation, and the operation cost of the microgrid is reduced.