The invention provides a high-temperature resistant and saturated-salt resistant biomass lubricant. The biomass lubricant comprises the following components in parts by weight: 60-80 parts of lauryl alcohol alkyl ether, 13-37 parts of a potassium oleate solution, 2-5 parts of an emulsifier and 1-2 parts of a tackifier. The lauryl alcohol alkyl ether and potassium oleate solution in the lubricant provided by the invention are synergistic, and through mutual match and synergy of the lauryl alcohol alkyl ether and potassium oleate solution, the obtained lubricant can have effects of high-temperature resistance and saturated-salt resistance. In addition, the lubricant provided by the invention is green and non-toxic, is biologically decomposed easily, is especially suitable for oil and gas wells with deep reservoir burial, high temperature and high pressure, and is suitable for operations of special wells such as extended reach wells, inclined wells, horizontal wells and the like. The invention also provides a preparation method of the high-temperature resistant and saturated-salt resistant biomass lubricant related to the technical scheme.