The invention discloses a three-dimensional movement deformation measurement system and an application thereof in a three-dimensional similar simulation experiment, and belongs to the technical fieldof similar simulation experiments in mining engineering. The main structure comprises a surface movement deformation measurement system and a three-dimensional simulation experiment table for holdinga similar simulation material, the surface movement deformation measurement system comprises a frame body, a lateral slide rail, a measurement head, a wireless data collector and a computer data processing system; by defining the structures and positions of specific components of the surface movement deformation measurement system, movement deformation values at different positions on the surfaceof a three-dimensional similar material model can be observed in a timely, true, accurate and all-round manner during the experiment, the measured data are transmitted to the data collector in real time, and a surface movement deformation value is displayed on a computer screen in real time after the processing of the computer data processing system; and in the measurement system disclosed by theinvention, the alignment of the measurement head and the measurement, transmission and processing of data are automatically and synchronously performed to avoid personal errors.