The invention discloses formula essential oil for treating hyperplasia of mammary glands. The formula essential oil is compounded from rose essential oil, mint essential oil, evening primrose essential oil, sweet orange essential oil and Jojoba oil, wherein the mint essential oil is used as a penetration enhancer, and transdermic absorption is achieved. As an external use medicine for treating cyclomastopathy, the formula essential oil greatly increases the use comfort degree, and abuses of oral medicines are avoided. During clinical testing, VAS score, tumor size score, tumor texture score and traditional Chinese medicine syndrome score of a rose and mint breast relieving essential oil treatment group are obviously reduced than those before treatment, but have significant differences, which indicates that the rose and mint breast relieving essential oil has significant treatment effects in the respects of alleviating breast pain, narrowing lumps in the breast, improving tumor textureand improving traditional Chinese medical science symptoms, the total effective rate of clinic curative effects is 100%, and the clinic curative effects are good.