The invention provides a CAN control box of an automobile air conditioner. The control box comprises a control box cover plate, a PCB and a control box shell; clamping rings perpendicular to the bodyof the control box cover plate are arranged on the side wall of the control box cover plate; clamping buckles connected with the clamping rings in a clamped mode are arranged on the outer walls of theopen end of the control box shell; the control box cover plate is clamped to the control box shell in a covering mode through the clamping rings and the clamping buckles, so that an installation cavity can be formed; the PCB is arranged in the installation cavity; grooves are formed in the periphery of the end surface of the covering side of the control box cover plate; sealing rings are arrangedin the grooves; and the sealing rings and the control box cover plate are of a secondary injection-molded structure. According to the CAN control box of the automobile air conditioner of the invention, the control box cover plate and the sealing rings are of the secondary injection-molded structure, therefore, the waterproof performance of the CAN control box is reliable; the shell is fixedly covered with the cover plate in a buckled mode through the clamping buckles. The CAN control box has the advantages of structure simple, installation convenient and low production cost investment.