The invention discloses a preparation technology of a traditional Chinese medicine preparation for treating cyclomastopathy. The preparation technology comprises the steps of thoroughly cleaning raw materials, respectively performing frozen storage, performing drying, performing breaking, then adding ethanol, performing soaking treatment, performing ultrasonic treatment with the ethanol to enablethe ethanol to impregnate into raw material cells, extracting effective substances, and performing enzymolysis, so that after cell walls are broken, effective substances can be released; and after filtration, performing concentration to obtain extractum, and preparing the extractum into the preparation. According to the preparation technology of a traditional Chinese medicine preparation for treating cyclomastopathy, provided by the invention, the preparation technology is simple to operate, effective components are sufficient to extract, the extraction speed is high, and the prepared preparation is convenient to use, free from side effects and low in cost.