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发明公开
CN110747194A 一种小分子多聚脱氧核糖核苷酸及其制备与应用 无效 - 撤回

一种小分子多聚脱氧核糖核苷酸及其制备与应用
摘要：
本发明针提供一种分子量集中于其功效区间的三文鱼小分子多聚脱氧核糖核苷酸(Small molecule polydeoxyribonucleotide,SMPDRN)产品及其可控精准制备方法，以及其在化妆品、药品、营养食品、保健食品领域的应用。本发明中的小分子多聚脱氧核糖核苷酸的分子量为50bp～1000bp，其分子量位于50bp～500bp片段的质量占其总质量的的85％以上。本发明中的SMPDRN的分子量集中于高功效范围，针对性更强，功效更稳定，获得的产品经细胞、动物、人体实验证实在提高细胞活性、促进胶原蛋白合成、使受损皮肤再生、促进伤口愈合、紧致皮肤、增加皮肤弹性、消除皱纹、延缓皮肤衰老、抗氧化并防止色斑形成、抗炎、修复受损细胞等方面均具有显著效果，优于现有PDRN产品。
摘要（英）：

The invention provides a salmon small molecule polydeoxyribonucleotide (SMPDRN) product with a molecular weight concentrated in an efficacy range of the salmon small molecule polydeoxyribonucleotide product, a controllable precise preparation method of the salmon small molecule polydeoxyribonucleotide product, and application of the salmon small molecule polydeoxyribonucleotide product to the fields of cosmetics, medicine, nutritious food and health food. The molecular weight of small molecule polydeoxyribonucleotide is 50-1000 bp, and the mass of the molecular weight of the small molecule polydeoxyribonucleotide at the 50-500 bp fragment accounts for more than 85% of the total mass of the small molecule polydeoxyribonucleotide; and the molecular weight of the SMPDRN is concentrated in thehigh-efficacy range, the pertinence is higher, the efficacy is more stable, and the obtained product has significant effects in improving cell activity, promoting collagen synthesis, regenerating damaged skin, promoting wound healing, tightening skin, increasing skin elasticity, eliminating wrinkles, delaying skin aging, resisting oxidation, preventing formation of color spots, resisting inflammation, repairing damaged cells and other aspects by being verified by cell, animal and human experiment, and is better than an existing PDRN product.

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