The invention discloses a preparation method of a high-strength vibration-resistant structural adhesive and a reaction kettle for producing the structural adhesive. The method comprises the followingsteps: a, adding alpha-methyl methacrylate, 2-hydroxyethyl methacrylate, trimethylolpropane trimethacrylate and methacrylic acid into a reaction kettle for stirring and mixing to obtain a mixture I; b, adding hydroquinone and disodium ethylenediamine tetraacetic acid into the mixture I obtained in the step a, and continuously stirring to obtain the mixture II; c, adding polyurethane modified acrylate and chloroprene rub into that mixture (II) prepared in the step (b), stirring and dissolving uniformly to obtain the mixture (III); d, adding the additive into the mixture III prepared in the stepc, and then performing vacuum defoaming to obtain the component A. According to the invention, the production of the structural adhesive is simpler, the cost is reduced, and at the same time, the prepared structural adhesive has better adhesion, stronger toughness and is not easy to break.