The invention discloses a multi-working-condition suspension cable spanning structure simulation test device that comprises a valve, a liquid storage tank and a suspension cable spanning pipe bridge;one end of the liquid storage tank is connected with a third valve, and the other end is connected with a circulating pump; the other end of the circulating pump is connected with a flow control loop;the other end of the flow control loop is connected with a flow meter; the other end of the flow meter is connected with a first pressure gauge; the other end of the first pressure gauge is connectedwith the suspension cable spanning pipe bridge; a plurality of groups of temperature self-compensating strain sensors are attached to the suspension cable spanning pipe bridge; the temperature self-compensating strain sensor is linearly connected with a demodulator; the demodulator is linearly connected with a data storage device, the data storage device is linearly connected with a mobile powersupply assembly, the other end of the suspension cable spanning pipe bridge is connected with a second pressure gauge, the other end of the second pressure gauge is connected with a back pressure valve, and the other end of the back pressure valve is connected with the third valve.