The invention discloses a method and device for adjusting a unit comprising power supply section regions. The method comprises the steps of: firstly obtaining a comparison section load rate of a to-be-partitioned section in actual dispatching operation, and dividing the to-be-partitioned section into a normal region, a help region, an emergency region and an out-of-limit region according to the comparison section load rate, adjusting and controlling the units in the normal region, the help region and the emergency region to obtain a unit adjusting amount corresponding to each region, and adopting an active adjusting mode to control the unit in the out-of-limit region to obtain the corresponding unit adjusting amount and the unit output in the region. According to the method, the section isdivided into the normal region, the help region, the emergency region and the out-of-limit region according to the section active power, the set section limit value, the normal region limit value andthe secondary emergency region limit value, and each region has a corresponding automatic adjustment mode, so that the workload of scheduling personnel is reduced, and the section condition judgmentaccuracy is improved to a certain extent.