The invention relates to a plant raw material rich in linoleic acid grease and a comprehensive utilization method. According to the method, Euscaphis konishii fruits or seeds are taken as a raw material, and Euscaphis konishii seed linoleic acid grease is extracted by adopting a traditional solvent reflux extraction method, wherein the specific parameters are as follows: an extraction solvent is n-hexane, the extraction temperature is 80-85 DEG C, and the extraction time is 55-65 minutes. The extraction rate of the linoleic acid-rich grease prepared by the extraction process is 31.4%-38.5%, and the linoleic acid content of the obtained grease is 64.5%-73.5%; and by drying the fruit or seed powder from which the grease is extracted, a powdery medicine for resisting raw lacquer allergy is prepared. The resource is rich, the production cost is low, and the obtained product can be used for industries such as medicine, health care products and food.