The invention relates to a cooling and heat dissipation system of an epoxy pouring type high frequency transformer. The system comprises a first heat exchange heat pipe, a second heat exchange heat pipe, a plate-fin heat exchanger, a ceramic connector, a refrigerant and a metal plate type material. The metal plate type material is arranged on the periphery of the heat-generating component in the high frequency transformer. One end of the first heat exchange heat pipe is fixed on the metal plate material, and the other end is connected with one end of the second heat exchange heat pipe throughthe ceramic connector. The other end of the second heat exchange heat pipe is connected with a plate-fin heat exchanger. The refrigerant is placed in the first heat exchange heat pipe or the second heat exchange heat pipe. According to the scheme, the epoxy casting type high frequency transformer is cooled, the hidden dangers of water leakage, oil leakage and the like are avoided, and the pipelines laid inside the transformer in the system are made of metal conductive materials and can be fixed at the same potential with adjacent iron cores or windings, thus ensuring that there is no suspension potential inside the transformer, reducing the partial discharge theory of the high frequency transformer and ensuring its long-term safe and stable operation.