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发明公开
CN1291974A 环己二醇衍生物 失效 - 权利终止 转让

环己二醇衍生物
摘要：
式Ⅰ化合物,其中X是C=CH2或CH2;Y和Z彼此独立地是氢、氟或羟基;A是－C≡C－,－CH=CH－或－CH2－CH2－;R1和R2彼此独立地是烷基或全氟烷基;R3是低级烷基;该化合物可用于过度增生性皮肤疾病的治疗或预防,特别是牛皮癣、基底细胞癌、角化症状和角化病;或者用于逆转与光照损伤有关的症状。
摘要（英）：

Compounds of formula IwhereinX is C=CH2 or CH2;Y and Z are independently of each other hydrogen, fluorine or hydroxy;A is -C=C-, -CH=CH- or -CH2-CH2-,R1 and R2 are independently of each other alkyl or perfluoroalkyl; andR3 is lower alkylare useful in the treatment or prevention of hyperproliferative skin diseases, particularly psoriasis, basal cell carcinomas, disorders of keratinization and keratosis; or for reversing the conditions associated with photodamage.

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