A high voltage DC power source program control system contains a micro-computer control unit, a high voltage DC power source program control unit exchanging information with the said micro-computer control unit. A microprocess unit is inside of the said program control unit controlled by its multiple parallel power sources units and multiple switch units connected with the output end of the said power source controlled by the adjustable power source unit of the said microprocessor unit. The system can provide continuous smooth adjustable DC power source from zero V to the highest voltage to electric appliances with security and reliability.