A sewing machine includes a needle bar (11) holding a sewing needle (19) having an eye hole (19a), a needle threading mechanism (17) including a threading hook (74) passing a needle thread (10) through the eye hole (19a) of the sewing needle, a presser bar (12) with a presser foot (20) attached to its lower end, a vertically moving mechanism (80) vertically moving the presser bar (12), a drive mechanism (83) driving the vertically moving mechanism (80), a threading operation unit (25) operating the needle threading mechanism (17), and a drive mechanism controlling unit (C) controlling the drive mechanism (83) vertically moving the presser bar (12) to a position where interference between the presser foot (20) and threading hook (74) is avoided when the needle threading operation unit (25)unit is operated.