This invention relates to an anti-sulphuric drill rod and a method for preparation of it, and it belongs to the scientific and technical sphere of oil drill rod. The component of steel used in it is following: C:0.25-0.38,Cr:0.80-3.80,Mo:0.15-0.65,V:0-0.08,Ti:0-0.06, B:0-0.06,Ni:0.10-0.35,Mn:0.40-0.90,Si:0.17-0.40,S:<0.010,P:<0.015, the remainder is Fe, and their units are mass percent. The method for preparation of it is following: heating the steel pipe of said component to 1000-1200 degrees, and making two ends become thick to get drill rod; then doing heat treatment to the whole rod, the process of heat treatment is quenching and high tempering. The quenching medium is water, with 860+-10 degrees temperature, and the insulating time is not less than 20 minutes. The tempering temperature is more than 500 degrees, and the insulating time is not less than 60 minutes. The drill rod produced with the method has the process of quenching, so its anti-corrosion capability to hydrogen sulfide is higher than general API drill rod and it can satisfy the needs of extracting acid oil.