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发明公开
CN1850847A 一种杠柳苷元的制备方法 无效 - 驳回

一种杠柳苷元的制备方法
摘要：
本发明公开了一种杠柳苷元的制备方法，其步骤为：(1)对含有杠柳毒苷的原料进行酸水解和收集，得到中间体A；(2)将中间体A进行柱层析，浓缩干燥后得到中间体B；(3)将中间体B重结晶或高效液相制备得到纯度为90％～100％的杠柳苷元。应用本发明的方法制备杠柳苷元，将原料中的杠柳毒苷水解为杠柳苷元后再进行萃取和柱层析，因此收率高，工艺简单，降低了有机溶剂用量，成本低，可实现工业化生产。
摘要（英）：

The invention discloses a manufacture method for periplocin that includes the following steps: taking acid hydrolysis to the raw material containing periplocin and collecting to gain intermediate A; taking column chromatography to the intermediate A and concentrating and drying to gain intermediate B; taking recrystallization and high efficient liquid phase gaining periplocin that has purity of 90%-100%. The invention has high yield, and has simple technology, low cost and could realize industrializing producing.

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