The invention relates to a combined cosmetic or therapeutic preparation comprising a support system consisting of membrane-forming lipids and at least two active ingredients. The aim of the invention is to provide a preparation, whose action covers the entire symptomatic complex that is associated with vessel wall insufficiency. To achieve this, the two or more active ingredients are selected from at least two of the following groups: (a) anti-coagulants; (b) vasoprotective agents; and (c) substances that promote microcirculation.